Presentation
Main domain: Neurophysiology
Subdomain: Clinical & translational neurosciences
Marie VIDAILHET & Stéphane LEHÉRICY’s team aims at further investigating network dysfunctions in movement and behavioral disorders using translational, neuroimaging, neurophysiological, and genetic/metabolic approaches from animals to patients.
The four main objectives are:
- To explore motor pathways in dystonia (AMEDYST)
- To investigate high order motor integration disorders (Agent10, COGIT) and motor consolidation during sleep (MEMOdream).
- To perform a prospective study (ICEBERG) aiming to build a dynamic progression model of PD for predictive medicine.
- To develop innovative therapeutic approaches in movement disorders using focused ultrasound, non-invasive stimulation and drugs targeting metabolic dysfunctions.
Major publications
- Biondetti E, Gaurav R, Yahia-Cherif L, Mangone G, Pyatigorskaya N,…, Vidailhet M, Lehéricy S Spatiotemporal changes in substantia nigra neuromelanin
content in Parkinson’s disease. Brain. 2020 Aug 28:awaa216.
- Mochel F, Delorme C, Czernecki V, …, Roze E, Labauge P, Nguyen S. J Haematopoietic stem cell transplantation in CSF1R-related adult-onset leukoencephalopathy with
axonal spheroids and pigmented glia. Neurol Neurosurg Psychiatry. 2019 Dec;90(12):1375-1376.
- Dizeux A, Gesnik M, Ahnine H, Blaize K, Arcizet F, Picaud S, Sahel JA, Deffieux T, Pouget P, Tanter M. Nat Commun. 2019 Mar 28;10(1):1400.
- Lacaux C, Izabelle C,…, Arnulf I, Oudiette D. Increased creative thinking in narcolepsy. Brain. 2019 Jul 1;142(7):1988-1999.
- Kemlin C, Moulton E, Lamy JC,…, Brochard V, Corvol JC, Samson Y, Rosso C. Elucidating the Structural and Functional Correlates of Upper-Limb Poststroke Motor Impairment. Stroke. 2019 Dec;50(12):3647-3649.
- Méneret A, Franz EA, Trouillard O,…, Brice A, Chédotal A, Dusart I, Roze E, Markie D.J Mutations in the netrin-1 gene cause congenital mirror movements. J Clin Invest. 2017 Nov 1;127(11):3923-3936.
- Sliwa J, Freiwald WA. A dedicated network for social interaction processing in the primate brain. Science. 2017 May 19;356(6339):745-749.
- Gallea C., Popa T,…, Fernández-Vidal S., Bardinet E., Roze E., Lehéricy S., Vidailhet M., Meunier S. Intrinsic signature of essential tremor in the cerebello-frontal network. Brain. 2015 Oct;138(Pt 10):2920-33.
Contact
marie.vidailhet@icm-institute.org
stephane.lehericy@icm-institute.org
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Team members
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Andreas HARTMANN
Principal Investigator, MD, PhD, PH, AP-HP
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Cecile GALLEA
Principal Investigator, PhD, CR1, CNRS
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Charlotte Rosso
Principal Investigator, MD, PhD, MCU-PH, Sorbonne University, AP-HP
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Delphine OUDIETTE
Principal Investigator, PhD, CR, INSERM
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Elodie HAINQUE
Hospital practitioner
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Emmanuel FLAMAND ROZE
Principal Investigator, MD, PhD, PU-PH, Sorbonne University, AP-HP
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Emmanuelle APARTIS-BOURDIEU
Clinician, MD, PhD, PU-PH
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Fanny MOCHEL
Principal Investigator, MD, PhD, MCU-PH, Sorbonne University, AP-HP
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Isabelle ARNULF
Principal Investigator, MD, PhD, PU-PH, Sorbonne University, AP-HP
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Julia SLIWA
Principal Investigator, PhD, CR, CNRS
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Nadya PYATIGORSKAYA
Clinician, MD, PhD, PH
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Pierre POUGET
Principal Investigator, PhD, CR1, CNRS
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Yulia Worbe
Principal Investigator, MD, PhD, PH, Sorbonne University, AP-HP
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Asya EKMEN
PhD Student
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Aurelie MENERET
Hospital practitioner
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Cyril ATKINSON-CLEMENT
Postdoctorant, PhD
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Célia LACAUX
PhD Student
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Charlotte Rosso
Principal Investigator, MD, PhD, MCU-PH, Sorbonne University, AP-HP
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Chetan Kumar VELUMURUGAN
Engineering assistant
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Denise BINGOBALI
Research engineer
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Domitille Gras
neuropediatrician and clinical research engineer
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Emma CHABANI
PhD Student
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Emma WAGNER
engineering assistant
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Julie ROYO
PhD
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Laetitia JEANCOLAS
Postdoctorant - PhD
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Lina DAGHSEN
PhD student
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Lydia CHOUGAR
PhD student
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Magali BARBIER
Technician
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Mariana Atencio Segura
Dietician
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Marie Pierre LUTON
Research engineer
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Oriane TROUILLARD
Engineering and technical staff
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Quentin WELNIARZ
Research engineer
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Rahul GAURAV
Research engineer, PhD
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Ruiyi YUAN
PhD student
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Sabine MEUNIER
Researcher, PhD, CR émérite
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Sandy MOURNET
PhD student
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Théophile BIETH
PhD Student
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Thomas ANDRILLON
PhD, CR1 - Inserm
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Thomas ORSET
PhD student
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Yannis IDIR
PhD student
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