Équipe Scientifiques

Page précédente Michel THIEBAUT DE SCHOTTEN Principal Investigator Equipe "FRONTlab : Systèmes frontaux : fonctions et dysfonctions" http://www.bcblab.com https://twitter.com/MichelTdS

Biographie

Thiebaut de Schotten M. a découvert que le syndrome neurologique de négligence visuelle est la conséquence d'une déconnexion des réseaux du cerveau entre les lobes frontal et pariétal de l’hémisphère droit (Science 2005). Il a réussi à cartographier par la suite toutes les principales connexions de la substance blanche supportant les échanges au sein des réseaux cérébraux chez l’homme (Nature Neuroscience 2011, Atlas of Human Brain connections 2012) et a démontré que le dysfonctionnement des réseaux cérébraux est le dénominateur commun aux désordres du comportement et de la cognition (Cerebral Cortex 2015). Ses avancées théoriques lui ont permis de developper un logiciel qui quantifie la déconnexion des réseaux cérébraux suite aux lésions cérébrales (http://toolkit.bcblab.com) et ainsi mettre à disposition gratuitement ses outils scientifiques (Cerebral Cortex 2014a). Dans ses récents travaux, Michel Thiebaut de Schotten a mis en évidence l'existence d’une plasticité des réseaux cérébraux à l’age adulte, ainsi les adultes peuvent changer la force de leur connexions cérébrales lors de nouveaux apprentissages (Cerebral Cortex 2014b). Il a mis en évidence les principes de vicariance permettant la récupération du cerveau, ainsi une région cérébrale saine partageant des connexions similaires à une région lésée peut prendre le relais et suppléer avec succès cette région (Brain 2015, Neuropsychologia 2016). En comparant les réseaux cérébraux entres les espèces il a également pu découvrir quelques règles de l’évolution phylogénétique des connexions cérébrales. Ainsi il a pu mettre en evidence un développement morphologique considérable des connexions cérébrales dédiées aux récentes fonctions comme le langage et la préservation surprenante des connexions pour les fonctions partagées entre les espèces comme la perception de l'espace (Cortex 2012). Enfin dans ses travaux les plus récents, Michel Thiebaut de Schotten utilise les réseaux cérébraux pour lire l’organisation fonctionnelle cérébrale à l’échelle de l’individu (Cerebral Cortex 2016) permettant à son équipe, pour la première fois, de construire un modèle fonctionnel sur mesure basé sur l’anatomie des réseaux de chaque cerveau.

Publications

  1. Croxson PL, Forkel SJ, Cerliani L, Thiebaut de Schotten M. Structural variability across the primate brain. (submitted)
  2. Mandonnet E, Cerliani L, Siuda-Krzywicka K, Zhi N, Volle E, Thiebaut de Schotten M. A case report of cognitive flexibility impairment after surgery of a right temporo-parietal glioma: how to reconcile lesional localisationism with physiological hodotopism (submitted)
  3. Su M, Zhao J, Thiebaut de Schotten M, Zhou W, Gong G, Ramus F, Hua S. Alterations in white matter pathways underlying phonological and morphological processing in Chinese developmental dyslexia (submitted)
  4. Chica A, Thiebaut de Schotten M, Bartolomeo P, Paz-Alonso PM. White matter microstructure of the Superior Longitudinal Fasciculus influences the interactions between attention and consciousness (submitted)
  5. Assaf Y, Johansen Berg H, Thiebaut de Schotten M. The role of diffusion MRI in neuroscience (submitted)
  6. Sanda N, Cerliani L, Authié CN, Sabbah N, Sahel JA, Habas C, Safran AB, Thiebaut de Schotten M. Visual brain plasticity induced by central and peripheral visual field loss (submitted)
  7. Sandrone S, Thiebaut de Schotten M, Reimann K, Troakes C, Bodi I, Lacerda L, Murphy DG, Geyer S, Catani M, Dell’Acqua F. Myelin mapping of the corpus callosum: discrepancy between  in vivo T1-weighted/T2-weighted Magnetic Resonance Imaging and post-mortem histology (submitted)
  8. Howells H, Thiebaut de Schotten M, Dell’Acqua F, Zappalà G, Leslie A, Simmons A, Murphy DG, Catani M. A direct link between asymmetry of brain networks, hand preference and manual dexterity. (submitted)
  9. Garcin B, Urbanski M, Thiebaut de Schotten M, Levy R, Volle E. Anterior temporal lobe morphometry predicts categorization ability. (submitted)
  10. Dalla Barba G, Brazzarola M, Barbera C, Marangoni S, Causin F, Bartolomeo P, Thiebaut de Schotten M. Different patterns of confabulation in left visuo-spatial neglect. (submitted)
  11. Lopez-Barosso D, Thiebaut de Schotten M, Amemiya E, Braga L, Dehaene S, Cohen L. The impact of schooling and literacy on the functional connectivity of vision and language-related networks. Cerebral Cortex (in revision) (IF: 8.29)
  12. Thiebaut de Schotten M, Shallice T. Same, similar or different? Is a single brain model sufficient? Cortex (2016) (IF: 4.31)
  13. Zeestraten EA, Gudbrandsen M, Daly E, Thiebaut de Schotten M, Catani M, Lai M, Ruigrok ANV, Lombardo MV, Chakrabarti B, Baron-Cohen S, Ecker C,MRC AIMS Consortium, Murphy DGM, Craig MC. Sex/Gender Differences in Frontal Lobe Connectivity in Adults with High Functioning Autism Spectrum Conditions. Translational Psychiatry (2016) (IF: 5.54)
  14. Parlatini V, Catani M, Dell’Acqua F, Simmons A, Radua J, Murphy D, Thiebaut de Schotten M. Functional segregation and integration within fronto-parietal networks. Neuroimage (2016) (IF: 5.46)
  15. Cerliani L, D’Arceuil H., Thiebaut de Schotten M. Connectivity-based parcellation of the macaque frontal cortex, and its relation with the cytoarchitectonic distribution described in current atlases. Brain Structure and Function (2016) (IF: 5.81)
  16. Thiebaut de Schotten M, Urbanski M, Batrancourt B, Levy R, Dubois B, Cerliani L, Volle E. Rostro-caudal architecture of the frontal lobes in humans. Cerebral Cortex (2016) (IF: 8.29)
  17. Bartolomeo P and Thiebaut de Schotten M. Let the left brain know what the right brain does: inter-hemispheric compensation of functional deficits after brain damage. Neuropsychologia (2016) (IF: 2.99)
  18. Sanefugi M, Craig M, Parlatini V, Metha M, Murphy DGM, Catani M, Thiebaut de Schotten M. Double-Dissociation between the mechanism leading to impulsivity and inattention in Attention Deficit Hyperactivity Disorder: a resting state functional connectivity study. Cortex (2016) (IF: 4.31)
  19. Ecker C, Andrews DS, Dalya E, Murphy C, Catani M, Dell’Aqua F, Thiebaut de Schotten M, Baron-Cohen S, Laib MC, Lombardo MV, Bullmore ET, Suckling J, Williams S, Jones D, Chiocchetti A, the MRC AIMS Consortium**, Murphy DGM. The relationship between cortical gyrification, white matter connectivity and Autism Spectrum Disorder. Cerebral Cortex (2016) (IF: 8.29)
  20. Urbanski M, Bréchemier ML, Garcin B, Bendetowicz D, Foulon C, Thiebaut de Schotten M, Rosso C, Clarençon F, Dupont S, Pradat P, Labeyrie MA, Levy R, Volle E. Reasoning by analogy requires the left frontal pole: lesion-deficit mapping and clinical implications. Brain (2016) (IF: 10.1)
  21. D’Anna L, Mesulam MM, Thiebaut de Schotten M, Wieneke C, Dell’Acqua F, Rogalski E, Catani M. Abnormalities of the uncinate fasciculus correlate with behavioral symptoms in primary progressive aphasia. Neurology (2016) (IF: 8.17)
  22. Catani M, Dell’Acqua F, Howells H, Budisavljevic S, Thiebaut de Schotten M, Froudist Walsh S, Bullmore ET, Suckling J, Baron-Cohen S, Lombardo MV, Wheelwright SJ, Chakrabarti B, Lai MC, Ruigrok ANV, Leemans A, Thompson A, Sandrone S, D’Anna L, Ecker C, MRC AIMS Consortium*, Craig M, Murphy DGM. Frontal networks in adults with autism spectrum disorder. Brain (2016) (IF: 10.1)
  23. Zhao J, Thiebaut de Schotten M, Altarelli I, Dubois J, Ramus F. Examination of white matter micro-structure in french developmental dyslexia: a spherical deconvolution tractography study. Cortex (2016) (IF: 4.31)
  24. Rojkova K, Volle E, Urbanski M, Humbert F, Dell’Acqua F, Thiebaut de Schotten M. Atlasing the frontal lobe connections and variability due to age and education: an advanced spherical deconvolution tractography study. Brain Structure and Function  (2016). (IF: 5.81)
  25. Froudist-Walsh S, Karolis V, Caldinellia C, Rodríguez-Toscano E,Tesse M, Thiebaut de Schotten M, Brittain PJ, Kroll J, Colquhoun M, Howes O, Dell’Acqua F,  Murray RM, William SCR, Nosarti C. Very early brain damage leads to remodelling of the working memory system in adulthood; a combined fMRI/tractography study. Journal of Neuroscience (2015) (IF: 5.92)
  26. Thiebaut de Schotten M, Dell’Acqua F, Ratiu P, Corkin S, Cabanis E, Iba-Zizen MT, Leslie A, Dronkers N, Plaisant O, Simmons A, Murphy D, Catani M.  From Phineas Gage to H.M.: Revisiting Disconnection Syndromes. Cerebral Cortex (2015) (IF: 8.29)
  27. Lunven M, Thiebaut de Schotten M, Duret C, Bourlon C, Migliaccio R, Bartolomeo P, Rode G, Bartolomeo P. White matter lesional predictors of chronic visual neglect: A longitudinal study. Brain (2015). (IF: 10.1)
  28. Aichelburg C, Urbanski M, Thiebaut de Schotten M, Levy R, Volle E. Neuroanatomical profile of analogical reasoning abilities. Cerebral Cortex (2014). (IF: 8.29)
  29. Bouhali F, Thiebaut de Schotten M, Pinel P, Poupon C, Mangin JF, Le Bihan D, Dehaene S, Laurent Cohen. Anatomical connections of the Visual Word Form Area. Journal of Neuroscience (2014) (IF: 5.92)
  30. Cavedo E, Lista S, Khachaturian Z, Aisen P, Amouyel P, Herholz K, Jack CR Jr, Sperling R, Cummings J, Blennow K, O'Bryant S, Frisoni GB, Khachaturian A, Kivipelto M, Klunk W, Broich K, Andrieu S, Thiebaut de Schotten M, Mangin JF, Lammertsma AA, Johnson K, Teipel S, Drzezga A, Bokde A, Colliot O, Bakardjian H, Zetterberg H, Dubois B, Vellas B, Schneider LS, Hampel H. The Road Ahead to Cure Alzheimer's Disease: Development of Biological Markers and Neuroimaging Methods for Prevention Trials Across all Stages and Target Populations. J Prev Alzheimers Dis. (2014) (IF: -)
  31. Lunven M, Thiebaut de Schotten M, Glize B, Jacquin-Courtois S, Cotton F, Bartolomeo P, Rode G. Effector-dependent, chronic disruption of spatial exploration after posterior brain damage and splenial disconnection Experimental Brain Research (2014) (IF: 2.06)
  32. Lecce F, Rotondaro F, Bonni S, Carlesimo A, Thiebaut de Schotten M, Tomaiuolo F and Doricchi F. Cingulate neglect in the human: disruption of contralesional reward learning in right brain damage. Cortex (2014) (IF: 4.31)
  33. Vergani F, Lacerda L, Martino J, Attems J, Morris C, Mitchell P, Thiebaut de Schotten M, Dell’Acqua F. White matter connections of the Supplementary Motor Area in humans. JNNP (2014). (IF: 6.43)
  34. Forkel SJ, Thiebaut de Schotten M, Dell’Acqua F, Kalra L, Murphy D, Williams S, Catani M. Right arcuate fasciculus volume predicts aphasia recovery. Brain (2014). (IF: 10.1)
  35. Radua J, Grau M, Canales-Rodriguez E, Thiebaut de Schotten M, Stein DJ, Catani M,  Mataix-Cols D. Multimodal meta-analysis of white matter abnormalities in obsessive-compulsive disorder. Neuropsychopharmacology (2014). (IF: 6.4)
  36. Bartolomeo P, Bachoud-Lévi AC, Thiebaut de Schotten M. Anatomy of cerebral achromatopsia: A reappraisal and comparison of two case reports. Cortex (2014). (IF: 4.31)
  37. Thiebaut de Schotten M, Valabregue R, Urbanski M, Bayle D, Volle E. Subdivision of the occipital lobes: an anatomical and functional MRI connectivity study. Cortex (2014). (IF: 4.31)
  38. Forkel SJ, Thiebaut de Schotten M, Danek A, Kawadler J, Dell’Acqua F, Catani M. the anatomy of fronto-occipital connections from early blunt dissections to contemporary neuroimaging. Cortex (2014). (IF: 4.31)
  39. Thiebaut de Schotten M, Cohen L, Amemiya E, Braga L, Dehaene S. Learning to read improves the structure of the arcuate fasciculus. Cerebral Cortex (2014). (IF: 8.29)
  40. Thiebaut de Schotten M, Tomaiuolo F, Aiello M, Merola S, Lecce F, Bartolomeo P, Doricchi F. Damage to white matter pathways in chronic spatial neglect. Cerebral Cortex (2014). (IF: 8.29)
  41. Catani M, Dell’Acqua F, Thiebaut de Schotten M. A Limbic System for memory and emotions. Neuroscience & Biobehavioral Reviews  (2013). (IF: 8.58)
  42. Catani M, Thiebaut de Schotten M, Slater D, Dell’Acqua F. Connectomic approaches before the connectome. Neuroimage (2013). (IF: 5.46)
  43. Catani M, Mesulam MM, Jakobsen E, Malik F, Wieneke C, Thompson CK, Thiebaut de Schotten M, Dell’Acqua F., Weintraub S, Rogalski E. A novel frontal pathway underlies verbal fluency deficits in Primary Progressive Aphasia. Brain  (2013). (IF: 10.1)
  44. Catani M, Dell’Acqua F, Bizzi A, Forkel S, Williams S, Simmons A, Murphy D and Thiebaut de Schotten M. Beyond cortical localization in clinico-anatomical correlation. Cortex (2012). (IF: 4.31)
  45. Chica, A.B., Thiebaut de Schotten M, Toba M, Malhotra P, Lupiáñiez R and Bartolomeo P. Attention networks and their interaction after right-hemisphere damage. Cortex (2012). (IF: 4.31)
  46. Hayman LA, Kumar VA, Hamilton J, Prabhu SS, Thiebaut de Schotten M, Al-Zubidi N, Pagani J, Vabulas M, Groneman M, Kumar AJ. Deformable Anatomic Templates Embed Knowledge Into Patient's Brain Images: Part 1. Construction and Display. Journal of Computer Assisted Tomography (2012). (IF: 1.47)
  47. Bartolomeo P, Thiebaut de Schotten M, Chica A.B. Brain Networks of visuospatial attention and their disruption in visual neglect. Frontier in Neuroscience (2012). (IF: 3.63)
  48. Bourgeois A, Chica AB, Migliaccio R, Thiebaut de Schotten M, Bartolomeo P. Cortical control of inhibition of return: evidence from patients with inferior parietal damage and visual neglect. Neuropsychologia (2012). (IF: 2.99)
  49. Thiebaut de Schotten M. Right brain dominance for visuospatial attention analysed with diffusion tractography. Medecine science (2012). (IF: 0.67)
  50. Catani M, Dell’Acqua F, Vergani F, Valabregue R, Thiebaut de Schotten M. Short frontal lobe connections: proposal for a new nomenclature. Cortex (2012). (IF: 4.31)
  51. Thiebaut de Schotten M, Dell’Acqua F, Valabregue R and Catani M. Monkey to human comparative anatomy of the frontal lobe association tracts. Cortex (2012). (IF: 4.31)
  52. Zappala G, Thiebaut de Schotten M and Eslinger P.J. Traumatic Brain Injury and the frontal lobes: what can we gain with diffusion tensor imaging? Cortex (2012). (IF: 4.31)
  53. Thiebaut de Schotten M, Dell’Acqua F, Forkel SJ, Murphy DGM and Catani M. A lateralized brain network for spatial attention. Nature Neuroscience (2011). (IF: 16.72)
  54. Ius T, Angelini E, Mandonnet E, Thiebaut de Schotten M and Duffau H. Evidence for limitations of brain plasticity using a postsurgical probabilistic atlas: the crucial role of the subcortical white matter connectivity. Neuroimage (2011). (IF: 5.46)
  55. Kas A, Cruz de Souza L, Samri D, Bartolomeo P, Lacomblez L, Kalafat M, Thiebaut de Schotten M, Cohen L, Dubois B, Habert M-O and Sarazin M. Neural correlates of cognitive impairment in posterior cerebral atrophy. Brain (2011). (IF: 10.1)
  56. Urbanski M, Thiebaut de Schotten M, Rodrigo S, Oppenheim C, Touzé E, Meder J-F, Moreau K, Blanchard M, Loeper-Jeny C, Dubois B and Bartolomeo P. DTI-MR tractography of white matter damage in stroke patients with neglect. Experimental Brain Research (2011). (IF: 2.06)
  57. Thiebaut de Schotten M, ffytche D, Dell’acqua F, Pugliese L, Williams S, Murphy DGM and Catani M. Atlasing Location, Asymmetry and Inter-Subject Variability of White Matter Tracts in the Human Brain with MR Diffusion Tractography. Neuroimage (2011). (IF: 5.46)
  58. Andrade K, Samri D, Sarazin M, Cruz de Sousa L, Cohen L, Thiebaut de Schotten M, Dubois B and Bartolomeo P. Visual Neglect in Posterior Cortical Atrophy. BMC Neurology (2010). (IF: 2.97)
  59. Pugliese L, Catani M, Aimeis S, Dell’Acqua F, Thiebaut de Schotten M, Murphy C, Robertson D, Deeley Q, Daly E and Murphy DGM. The limbic system in asperger syndrome: A DTI-tractography Study. Neuroimage (2009). (IF: 5.46)
  60. Doricchi F, Thiebaut de Schotten M, Tomaiuolo F and Bartolomeo P. White matter disconnections and gray matter dysfonctions in visual neglect. Gaining insights into the brain networks of spatial awareness. Cortex (2008). (IF: 4.31)
  61. Volle E, Kinkingnéhun S, Pochon JB, Mondon K, Thiebaut de Schotten M, Renie L, du Boisgueheneuc F, Duffau H, Samson Y, Dubois B and Levy R. The functional architecture of the posterior and lateral prefrontal cortex in humans. Cerebral Cortex (2008).  (IF: 8.29)
  62. Thiebaut de Schotten M, Kinkingnéhun S, Delmaire C, Lehéricy S, Duffau H, Thivard L, Volle E, Levy R, Dubois B and Bartolomeo P. Visualization of disconnection syndromes in humans. Cortex (2008). (IF: 4.31)
  63. Catani M & Thiebaut de Schotten M. A diffusion tensor tractography Atlas for virtual dissections. Cortex (2008). (IF: 4.31)
  64. Urbanski M, Thiebaut de Schotten M, Rodrigo S, Catani M, Oppenheim C, Touzé E, Chokron S, Méder JF, Lévy R, Dubois B and Bartolomeo P. Brain network for spatial awareness: Evidence from diffusion tensor tractography. JNNP (2008). (IF: 6.43)
  65. Duffau H, Thiebaut de Schotten M and Mandonnet E. White matter functional connectivity as an additional landmark for dominant temporal lobectomy. JNNP (2008). (IF: 6.43)
  66. Urbanski M, Angeli V, Bourlon C, Cristinzio C, Ponticorvo M, Rastelli F, Thiebaut de Schotten M and Bartolomeo P. Unilateral spatial neglect: a dramatic but often neglected consequence of right hemisphere damage. Revue neurologique (2007).  (IF: 0.95)
  67. Bartolomeo P, Thiebaut de Schotten M. and Doricchi F. Left Unilateral neglect as a disconnection syndrome. Cerebral Cortex (2007). (IF: 8.29)
  68. Bartolomeo P, Thiebaut de Schotten M and Duffau H. Mapping of Visuospatial Functions during Brain Surgery: A New Tool to Prevent Unilateral Spatial Neglect. Neurosurgery (2007). (IF: 3.78)
  69. Thiebaut de Schotten M & Bartolomeo P. Neuro-anatomy of space processing. Medecine science (2006). (IF: 0.67)
  70. Thiebaut de Schotten M, Urbanski M, Duffau H, Volle E, Levy R, Dubois B and Bartolomeo P. Direct evidence for a parietal-frontal pathway subserving spatial awareness. Science (2005). (IF: 34.66)