Équipe Scientifiques

Previous page Stephane HAIK MD, PhD, DR2, INSERM Team “Alzheimer’s disease and prion diseases ” Contact by email

Biography

Stéphane Haïk is co-leader of the Alzheimer’s and Prion Diseases team at the ICM, Research Director at INSERM and coordinator of the French National Center of Reference for Unconventional Transmissible Agents. He received a MD in 1997 or University Paris V René Descartes and a PhD in Neurosciences in 2003. He received the “Prix de l’Internant/Paris-2000” and an Inserm Avenir Award 2005. He is a referee for numerous international journals and for National agencies involved in risk assessment and public health surveillance.

Research work

Neurobiology & neurology of prion and prion-like disorders

Marie-Claude Potier’s and Stéphane Haïk’s group aims at understanding the role of lipids, particularly cholesterol and ApoE, in the secretion and neuronal transport, of AB, their involvement in endosomal modifications that occur early during the course of the disease and novel mechanisms of AB toxicity identified in vivo. Stephane Haïk’s group studies the development of pre-mortem diagnostic procedures for Prion’s disease, the characterization of classical and emerging human prion strains, the understanding of the molecular and cellular mechanisms underlying prion strain selection, propagation and pathogenicity in the human brain.