Équipe Scientifiques

Page précédente Raffaella Lara MIGLIACCIO Principal Investigator Equipe "FRONTlab : Systèmes frontaux : fonctions et dysfonctions"


Dr. Raffaella Migliaccio obtained her medical degree and clinical specialty training in Neurology in Naples, Italy. To pursue her research on neurodegenerative patients, she spent a period of her doctorate training at the University of California, San Francisco (UCSF), Memory and Aging Center. While at UCSF, she worked on several cognitive and neuroimaging studies, on Alzheimer’s disease (AD) and frontotemporal dementia (FTD). In particular, she started to study early and atypical variants of AD, such as posterior cortical atrophy (PCA) and logopenic progressive aphasia (LPA). After she left UCSF, she earned her PhD degree (2009) and moved to Paris to be a post-doc at INSERM unit, in the Pitié-Salpêtrière Hospital. From 2015, Dr. Migliaccio is a CR1 Inserm (Associate Professor) at Institut du cerveau et de la moelle épinière (ICM), in the Pitié-Salpêtrière Hospital, Paris. She continues to study the early and atypical variants of AD, and in particular she focuses her research on the effect of pathological AD changes on functional neural networks, using MRI techniques. Moreover, she is going to extend this multi-modal research approach (clinical, cognitive, neuroimaging) to FTD.

Travaux de recherche

Original articles   Last or first author
  1. Teichmann M, Kas A, Boutet C, Ferrieux S, Nogues M, Samri D, Rogan C, Dormont D, Dubois B, Migliaccio R. Deciphering logopenic primary progressive aphasia: a clinical, imaging and biomarker investigation. Brain (2013) (IF 10.226).
  2. Migliaccio R, Gallea C, Kas A, Perlbarg V, Samri D, Trotta L, Michon A, Lacomblez L, Dubois B, Lehericy S, Bartolomeo P. Functional Connectivity of Ventral and Dorsal Visual Streams in Posterior Cortical Atrophy. J Alzheimers Dis. (2016) (IF 3.731).
  3. Migliaccio R, Boutet C, Valabregue R, Ferrieux S, Nogues M, Lehéricy S, Dormont D, Levy R, Dubois B, Teichmann M. The Brain Network of Naming: A Lesson from Primary Progressive Aphasia. PLoS One (2016) (IF 4.411).
  4. Migliaccio R, Agosta F, Possin KL, Canu E, Filippi M, Rabinovici GD, Rosen HJ, Miller BL, Gorno-Tempini ML. Mapping the progression of atrophy in early and late onset Alzheimer’s disease. J Alzheimers Dis. (2015) (IF 3.731).
  5. Migliaccio R, Bouhali F, Rastelli F, Ferrieux S, Arbizu C, Vincent S, Pradat-Diehl P, Bartolomeo P. Damage to the medial motor system in stroke patients with motor neglect. Front Hum Neurosc (2014) (IF 4.603).
  6. Migliaccio R, Agosta F, Possin K, Rabinovici GD, Miller BL, Gorno-Tempini ML. White Matter atrophy in Alzheimer Disease variants. Alzheimer and Dementia (2012) (IF 14.483).
  7. Migliaccio R, Agosta F, Scola E, Magnani G, Cappa SF, Pagani E, Canu E, Comi G, Falini A, Gorno-Tempini ML, Bartolomeo P, Filippi M. Ventral and dorsal visual streams in posterior cortical atrophy: A DT MRI study. Neurobiol Aging (2012) (IF 5.117).
  8. Migliaccio R, Agosta F, Toba MN, Samri D, Corlier F, de Souza LC, Chupin M, Sharman M, Gorno-Tempini ML, Dubois B, Filippi M, Bartolomeo P. Brain networks in posterior cortical atrophy: A single case tractography study and literature review. Cortex (2011) (IF 6.161).
  9. Migliaccio R, Agosta F, Rascovsky K, Karydas A, Bonasera S, Rabinovici GD, Miller BL, Gorno-Tempini ML. Clinical syndromes associated with posterior atrophy: early age of onset AD spectrum. Neurology (2009) (IF 8.286).
  Second or second-last
  1. Toba MN, Migliaccio R, Batrancourt B, Bourlon C, Duret C, Pradat-Diehl P, Dubois B, Bartolomeo P. Common brain networks for distinct deficits in visual neglect. A combined structural and tractography MRI approach. Neuropsychologia. 2017 Oct 18. pii: S0028-3932(17)30393-7. doi: 10.1016/j.neuropsychologia.2017.10.018. [Epub ahead of print]
  2. Teichmann M, Migliaccio R, Kas A, Dubois B. Logopenic progressive aphasia beyond Alzheimer's-an evolution towards dementia with Lewy bodies. J Neurol Neurosurg Psychiatry (2012) (IF 4.924).
  3. Vitali P, Migliaccio R, Agosta F, Rosen HJ, Geschwind MD. Neuroimaging in dementia. Semin Neurol (2008) (IF 1.642).
  4. Sorrentino G, Migliaccio R, Bonavita V. Treatment of vascular dementia: the route of prevention. Eur Neurol (2008) (IF 1.81).
  1. Yin RH, Tan L, Liu Y, Wang WY, Wang HF, Jiang T, Zhang Y, Gao J, Canu E, Migliaccio R, Filippi M, Gorno-Tempini ML, Yu JT. Multimodal Voxel-Based Meta-Analysis of White Matter Abnormalities in Alzheimer's Disease. J Alzheimers Dis. (2015) (IF 3.731).
  2. Caso F, Agosta F, Mattavelli D, Migliaccio R, Canu E, Magnani G, Marcone A, Copetti M, Falautano M, Comi G, Falini A, Filippi M. White Matter Degeneration in Atypical Alzheimer Disease. Radiology (2015) (IF 7.296).
  3. Bourgeois A, Chica AB, Migliaccio R, Bayle DJ, Duret C, Pradat-Diehl P, Lunven M, Pouget P, Bartolomeo P. Inappropriate rightward saccades after right hemisphere damage: oculomotor analysis and anatomical correlates. Neuropsychologia (2015) (IF 197).
  4. Lunven M, Thiebaut de Schotten M, Bourlon C, Duret C, Migliaccio R, Rode G, Bartolomeo P. White matter lesional predictors of chronic visual neglect: a longitudinal study. Brain (2014) (IF 10.226).
  5. Caroppo P, Belin C, Grabli D, Maillet D, De Septenville A, Migliaccio R, Clot F, Lamari F, Camuzat A, Brice A, Dubois B, Le Ber I. Posterior cortical atrophy as an extreme phenotype of GRN mutations. JAMA Neurology (2014) (IF 10.03).
  6. Lunven M, Thiebaut de Schotten M, Glize B, Migliaccio R, Jacquin-Courtois S, Cotton F, Bartolomeo P, Rode G. Effector-dependent neglect and splenial disconnection: a spherical deconvolution tractography study. Exp Brain Res. (2014) (IF 1.917).
  7. Serra M, La Corte V, Migliaccio R, Brazzarola M, Zannoni I, Pradat-Diehl P, Dalla Barba G. Confabulators mistake multiplicity for uniqueness. Cortex (2014) (IF 6.161).
  8. Quentin R, Chanes L, Migliaccio R, Valabrègue R, Valero-Cabré A. Fronto-tectal white matter connectivity mediates facilitatory effects of non-invasive neurostimulation on visual detection. Neuroimage (2013) (IF 6.252).
  9. Rastelli F, Tallon-Baudry C, Migliaccio R, Toba MN, Ducorps A, Pradat-Diehl P, Duret C, Dubois B, Valero-Cabré A, Bartolomeo P. Neural dynamics of neglected targets in patients with right hemisphere damage. Cortex (2013) (IF 6.161).
  10. Passamonti L, Fera F, Tessitore A, Russo A, Cerasa A, Gioia CM, Monsurrò MR, Migliaccio R, Tedeschi G, Quattrone A. Dysfunctions within limbic-motor networks in amyotrophic lateral sclerosis. Neurobiol Aging (2013) (IF 5.117).
  11. Caso F, Onofrio F, Falautano M, Todeschini P, Migliaccio R, Comi G, Perani D, Magnani G. From primary progressive aphasia to corticobasal syndrome: two clinical and rCBF functional reports. Neurocase (2012) (IF 1.114).
  12. Bourgeois A, Chica AB, Migliaccio R, Thiebaut de Schotten M, Bartolomeo P. Cortical control of inhibition of return: evidence from patients with inferior parietal damage and visual neglect. Neuropsychologia (2012) (IF 3.477).
  13. Kas A, de Souza LC, Samri D, Bartolomeo P, Lacomblez L, Kalafat M, Migliaccio R, Thiebaut de Schotten M, Cohen L, Dubois B, Habert MO, Sarazin M. Neural correlates of cognitive impairment in posterior cortical atrophy. Brain (2011) (IF 10.226).
  14. Charras P, Lupiáñez J, Migliaccio R, Toba M, Pradat-Diehl P, Duret C, Bartolomeo P. Dissecting the component deficits of perceptual imbalance in visual neglect: evidence from horizontal-vertical length comparisons. Cortex (2012) (IF 6.161).
  15. Johnson JK, Chang CC, Brambati SM, Migliaccio R, Gorno-Tempini ML, Miller BL, Janata P. Music recognition in frontotemporal lobar degeneration and Alzheimer disease. Cogn Behav Neurol. (2011) (IF 1.342).
  16. Agosta F, Henry RG, Migliaccio R, Neuhaus J, Miller BL, Dronkers NF, Brambati SM, Filippi M, Ogar JM, Wilson SM, Gorno-Tempini ML. Language networks in semantic dementia. Brain (2010) (IF 10.226).
  17. Agosta F,* Vossel KA,* Miller BL, Migliaccio R, Bonasera S, Filippi M, Boxer AL, Karydas A, Possin KL, Gorno-Tempini, ML. Apolipoprotein E epsilon4 is associated with disease-specific effects on brain atrophy in Alzheimer's disease and frontotemporal dementia. PNAS (2009) (IF 737).
  18. Nocentini U, Tedeschi G, Migliaccio R, Dinacci D, Lavorgna L, Bonavita S, Bresciamorra V, Comanducci G, Coniglio G, Livrea P, Mannu R, Orefice G, Paciello M, Patti F, Quattrone A, Salemi G, Savettieri G, Simone IL, Valentino P, Zappia M, Bonavita V, Musicco M, Caltagirone C. An exploration of anger phenomenology in multiple sclerosis. Eur J Neurol (2009) (IF 4.162).
  19. Tessitore A, Esposito F, Monsurrò MR, Graziano S, Panza D, Russo A, Migliaccio R, Conforti FL, Morrone R, Quattrone A, Di Salle F, Tedeschi G. Subcortical motor plasticity in patients with sporadic ALS: An fMRI study. Brain Res Bull (2006) (IF 2.935).
  20. Tartaglia MC, Vitali P, Migliaccio R, Agosta F, Rosen H. Neuroimaging in dementia. Continuum (Minneap Minn) (2010).
  Teaching papers
  1. Bartolomeo P and Migliaccio R (2016). Attention disorders. In: Cognitive Neurology and Dementia (Oxford Textbook in Clinical Neurology). Oxford University Press.
  2. Bartolomeo P, Bourgeois A, Bourlon C and Migliaccio R (2013). Visual and motor mental imagery after brain damage. In: Multisensory Imagery. Springer.
  3. Bartolomeo P, Migliaccio R (2011). I disturbi del riconoscimento: le agnosie. In: Manuale di Neuropsicologia: clinica ed elementi di riabilitazione, 2nd Edition (Vallar G, Papagno C, eds). Bologna: Il Mulino. Please note that a new version of this book is in preparation.
  4. Migliaccio R, Bourgeois A, Bartolomeo P (2011). Les Apraxies. In: Encyclopédie Médico-Chirurgicale: Neurologie.