Previous page Claire WYART PhD, CR1, INSERM Team “Sensory Spinal Signaling ”


Claire Wyart did her PhD between 2000 and 2003 in Strasbourg University in Biophysics working on small networks of controlled architecture. She performed her postdoc in UC Berkeley from 2005-2010, developing optogenetics in vivo in the zebrafish larva to probe the circuits underlying behavior in experimental models. Since 2011, she has lauched her team in the ICM with the label ATIP/Avenir, the ENP Chair of Excellence and the Emergence prize from the City of Paris.

Research work

Biophysique, neuroscience, physiologie et imagerie.
Claire Wyart’s team investigates the neuromodulatory pathway coming from the brain and within the spinal cord and its effects on locomotion and posture. The team is interested in the circuits referred to as reticulospinal neurons (RSNs) that trigger locomotion in the hindbrain. The main objectives are:
  • To study how inner physiological states via neuromodulation and release of peptides change the activity of RSNs and CSF-contacting neurons.
  • To pursue the investigation of the mechanisms linking CSF and body-axis formation, scoliosis and host defense.
  • To constitute new translational paths involving the Prof. Moussellard in order to provide new insights into the mechanisms of recovery after torsion of the spine, spinal injury or pathogen invasion in the CSF.