Research Teams

Filter results
Team “Gene Therapy”
Team leader(s)
Nathalie CARTIER MD, PhD, DRE, INSERM
Gene therapy
Main domain: Clinical & translational neurosciences
Subdomain : Molecular & cellular neuroscience

Nathalie CARTIER’s team develops gene therapy strategies for severe neurodegenerative diseases including Huntington's disease, Spinocerebellar ataxias, Alzheimer's disease and genetic leukodystrophies. Research includes proof of concept in animal models and translational steps to clinical applications.
The team aims to propose a phase I/II therapeutic trial in 2020 for Huntington disease. The team will also develop tools for the delivery of therapeutic molecules in the brain (use of microglia, optimization of AAV for intravenous administration, optogenerapy for time-controlled delivery). For more information
Team “Algorithms, Models and Methods for Images and Signals of the Human Brain ”
Team leader(s)
Olivier COLLIOT PhD, DR2, CNRS
Stanley DURRLEMAN PhD, DR2, INRIA
Methodology and neuroimaging
Main domain: Clinical & translational neurosciences

Olivier COLLIOT & Stanley DURRLEMAN’s team, the ARAMIS team aims to build numerical models of brain diseases from multimodal patient data based on the development of specific data-driven approaches.   The main research axes are
  • Integrate multimodal neuroimaging data (PET, microstructure, ASL) to fully characterize alterations
  • Model the temporal dynamics of disease
  • Model brain networks
  • Integrate imaging with other types of data (in particular omics and clinical data)
For more information