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Team “Myelin plasticity and regeneration”

Presentation

Repair
Main domain: Cellular & molecular neurosciences
Subdomain : Clinical & translational neurosciences

Brahim NAIT OUMESMAR & Violetta ZUJOVIC’s team aims at providing better insight into the mechanisms of myelin plasticity and regeneration. Compelling evidences indicate that oligodendrocyte progenitor cells (OPCs) sense neuronal activity and immune cells signaling, highlighting the importance of these crosstalk’s in (re)-myelination. Therefore, our research project will rely on three major aims to decipher:
  • The role of i)neuronal activity and ii) immune cells in oligodendrocyte differentiation, regeneration and myelin repair, unraveling their relevance in human oligodendrocyte differentiation;
  • To develop innovative tools to identify and assess the therapeutic value of new pro-myelinating compounds.

Major publications

Contact

violetta.zujovic@icm-institute.org
brahim.naitoumesmar@icm-institute.org

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Team members

  • Anne BARON VAN EVERCOOREN

    Principal Investigator, DR Emeritus, INSERM

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  • Lamia BOUSLAMA

    Principal Investigator, PhD, MCU, Sorbonne Université

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