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Team “Normal and abnormal motor control: movement disorders and experimental therapeutics”

Presentation

Basal ganglia, neurosurgery, movements disorders
Main domain: Neurophysiology
Subdomain: Clinical & translational neurosciences

Marie VIDAILHET & Stéphane LEHÉRICY’s team aims at further investigating network dysfunctions in movement and behavioral disorders using translational, neuroimaging, neurophysiological, and genetic/metabolic approaches from animals to patients.

 

The four main objectives are:

  • To explore motor pathways in dystonia (AMEDYST)
  • To investigate high order motor integration disorders (Agent10, COGIT) and motor consolidation during sleep (MEMOdream).
  • To perform a prospective study (ICEBERG) aiming to build a dynamic progression model of PD for predictive medicine.
  • To develop innovative therapeutic approaches in movement disorders using focused ultrasound, non-invasive stimulation and drugs targeting metabolic dysfunctions.

Major publications

Contact

marie.vidailhet@icm-institute.org
stephane.lehericy@icm-institute.org

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Team members

  • Andreas HARTMANN

    Principal Investigator, MD, PhD, PH, AP-HP

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  • Cecile GALLEA

    Principal Investigator, PhD, CR1, CNRS

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  • Charlotte Rosso

    Principal Investigator, MD, PhD, MCU-PH, Sorbonne University, AP-HP

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  • Delphine OUDIETTE

    Principal Investigator, PhD, CR, INSERM

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  • Emmanuel FLAMAND ROZE

    Principal Investigator, MD, PhD, PU-PH, Sorbonne University, AP-HP

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  • Fanny MOCHEL

    Principal Investigator, MD, PhD, MCU-PH, Sorbonne University, AP-HP

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  • Isabelle ARNULF

    Principal Investigator, MD, PhD, PU-PH, Sorbonne University, AP-HP

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  • Julia SLIWA

    Principal Investigator, PhD, CR, CNRS

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  • Pierre POUGET

    Principal Investigator, PhD, CR1, CNRS

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  • Yulia Worbe

    Principal Investigator, MD, PhD, PH, Sorbonne University, AP-HP

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